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geNOps[Bearbeiten | Quelltext bearbeiten]
The acronym geNOps stands for genetically encoded Nitric Oxide probes[1], a novel class of single fluorescent protein based Nitric Oxide (NO) reporters for live cell imaging of NO in individual cells[2]. geNOps are available in three different colours including cyan (ECFP), green (EGFP), and orange (mKusabira2) variants either non-targeted cytosolic[3], or targeted to the mitochondrial lumen[4].
- ↑ Emrah Eroglu, Benjamin Gottschalk, Suphachai Charoensin, Sandra Blass, Helmut Bischof: Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics. In: Nature Communications. Band 7, 4. Februar 2016, ISSN 2041-1723, doi:10.1038/ncomms10623, PMID 26842907, PMC 4743004 (freier Volltext) – (nature.com [abgerufen am 1. Januar 2017]).
- ↑ Marissa Opelt, Emrah Eroglu, Markus Waldeck-Weiermair, Michael Russwurm, Doris Koesling: Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin. In: Journal of Biological Chemistry. Band 291, Nr. 46, 11. November 2016, ISSN 0021-9258, S. 24076–24084, doi:10.1074/jbc.M116.752071, PMID 27679490, PMC 5104933 (freier Volltext) – (jbc.org [abgerufen am 1. Januar 2017]).
- ↑ Suphachai Charoensin, Emrah Eroglu, Marissa Opelt, Helmut Bischof, Corina T. Madreiter-Sokolowski: Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS). In: Free Radical Biology and Medicine. Band 102, 1. Januar 2017, S. 248–259, doi:10.1016/j.freeradbiomed.2016.11.049 (sciencedirect.com [abgerufen am 1. Januar 2017]).
- ↑ Nitric Oxide Probes (geNOps) Archives - Next Generation Fluorescence Imaging. In: Next Generation Fluorescence Imaging. Abgerufen am 1. Januar 2017 (amerikanisches Englisch).