„Glykogensynthasen“ – Versionsunterschied

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== Literatur ==
== Literatur ==
* Buschazzio A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM (August 2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation". EMBO J. 23 (16): 3196–3205. doi:10.1038/sj.emboj.7600324. PMC 514502. PMID 15272305.; rendered using PyMOL.
* Buschazzio A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM (August 2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation". EMBO J. 23 (16): 3196–3205. {{doi|10.1038/sj.emboj.7600324}}. {{PMC|514502}}. PMID 15272305.; rendered using PyMOL.
* Jentjens R, Jeukendrup A (2003). "Determinants of post-exercise glycogen synthesis during short-term recovery". Sports Med 33 (2): 117–44. doi:10.2165/00007256-200333020-00004. PMID 12617691.
* Jentjens R, Jeukendrup A (2003). "Determinants of post-exercise glycogen synthesis during short-term recovery". Sports Med 33 (2): 117–44. {{doi|10.2165/00007256-200333020-00004}}. PMID 12617691.
* Buchbinder JL, Rath VL, Fletterick RJ (2001). "Structural relationships among regulated and unregulated phosphorylases". Annu Rev Biophys Biomol Struct. 30 (1): 191–209. doi:10.1146/annurev.biophys.30.1.191. PMID 11340058.
* Buchbinder JL, Rath VL, Fletterick RJ (2001). "Structural relationships among regulated and unregulated phosphorylases". Annu Rev Biophys Biomol Struct. 30 (1): 191–209. {{doi|10.1146/annurev.biophys.30.1.191}}. PMID 11340058.
* Buschiazzo A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM (2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.". EMBO J. 23 (16): 3195–205. doi:10.1038/sj.emboj.7600324. PMC 514502. PMID 15272305.
* Buschiazzo A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM (2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.". EMBO J. 23 (16): 3195–205. {{doi|10.1038/sj.emboj.7600324}}. {{PMC|514502}}. PMID 15272305.
* Coutinho PM, Deleury E, Davies GJ, Henrissat B (2003). "An evolving hierarchical family classification for glycosyltransferases". J. Mol. Biol. 328 (2): 307–17. doi:10.1016/S0022-2836(03)00307-3. PMID 12691742.
* Coutinho PM, Deleury E, Davies GJ, Henrissat B (2003). "An evolving hierarchical family classification for glycosyltransferases". J. Mol. Biol. 328 (2): 307–17. {{doi|10.1016/S0022-2836(03)00307-3}}. PMID 12691742.
* Roach PJ (2002). "Glycogen and its Metabolism". Curr Mol Med 2 (2): 101–20. doi:10.2174/1566524024605761. PMID 11949930.
* Roach PJ (2002). "Glycogen and its Metabolism". Curr Mol Med 2 (2): 101–20. {{doi|10.2174/1566524024605761}}. PMID 11949930.
* Ball SG, Morell MK (2003). "From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule". Annu Rev Plant Biol 54 (1): 207–33. doi:10.1146/annurev.arplant.54.031902.134927. PMID 14502990.
* Ball SG, Morell MK (2003). "From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule". Annu Rev Plant Biol 54 (1): 207–33. {{doi|10.1146/annurev.arplant.54.031902.134927}}. PMID 14502990.
* Azpiazu I, Manchester J, Skurat AV, Roach PJ, Lawrence JC Jr (2000). "Control of glycogen synthesis is shared between glucose transport and glycogen synthase in skeletal muscle fibers". Am J Physiol Endocrinol Metab 278 (2): E234–43. PMID 10662707.
* Azpiazu I, Manchester J, Skurat AV, Roach PJ, Lawrence JC Jr (2000). "Control of glycogen synthesis is shared between glucose transport and glycogen synthase in skeletal muscle fibers". Am J Physiol Endocrinol Metab 278 (2): E234–43. PMID 10662707.
* Aschenbach WG, Suzuki Y, Breeden K, Prats C, Hirshman MF, Dufresne SD, Sakamoto K, Vilardo PG, Steele M, Kim JH, Jing SL, Goodyear LJ, DePaoli-Roach AA (2001). "The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise". J Biol Chem 276 (43): 39959–67. doi:10.1074/jbc.M105518200. PMID 11522787.
* Aschenbach WG, Suzuki Y, Breeden K, Prats C, Hirshman MF, Dufresne SD, Sakamoto K, Vilardo PG, Steele M, Kim JH, Jing SL, Goodyear LJ, DePaoli-Roach AA (2001). "The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise". J Biol Chem 276 (43): 39959–67. {{doi|10.1074/jbc.M105518200}}. PMID 11522787.
* Browner MF, Nakano K, Bang AG, Fletterick RJ (March 1989). "Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution". Proceedings of the National Academy of Sciences of the United States of America 86 (5): 1443–7. doi:10.1073/pnas.86.5.1443. PMC 286712. PMID 2493642.
* Browner MF, Nakano K, Bang AG, Fletterick RJ (March 1989). "Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution". Proceedings of the National Academy of Sciences of the United States of America 86 (5): 1443–7. {{doi|10.1073/pnas.86.5.1443}}. {{PMC|286712}}. PMID 2493642.
* Westphal SA, Nuttall FQ (February 1992). "Comparative characterization of human and rat liver glycogen synthase". Archives of biochemistry and biophysics 292 (2): 479–86. doi:10.1016/0003-9861(92)90019-S. PMID 1731614.
* Westphal SA, Nuttall FQ (February 1992). "Comparative characterization of human and rat liver glycogen synthase". Archives of biochemistry and biophysics 292 (2): 479–86. {{doi|10.1016/0003-9861(92)90019-S}}. PMID 1731614.
* Kollberg G, Tulinius M, Gilljam T, Ostman-Smith I, Forsander G, Jotorp P, Oldfors A, Holme E (October 2007). "Cardiomyopathy and exercise intolerance in muscle glycogen storage disease 0". The New England Journal of Medicine 357 (15): 1507–14. doi:10.1056/NEJMoa066691. PMID 17928598.
* Kollberg G, Tulinius M, Gilljam T, Ostman-Smith I, Forsander G, Jotorp P, Oldfors A, Holme E (October 2007). "Cardiomyopathy and exercise intolerance in muscle glycogen storage disease 0". The New England Journal of Medicine 357 (15): 1507–14. {{doi|10.1056/NEJMoa066691}}. PMID 17928598.
* Huang TS, Krebs EG (April 1977). "Amino acid sequence of a phosphorylation site in skeletal muscle glycogen synthetase". Biochem. Biophys. Res. Commun. 75 (3): 643–50. doi:10.1016/0006-291X(77)91521-2. PMID 405007.
* Huang TS, Krebs EG (April 1977). "Amino acid sequence of a phosphorylation site in skeletal muscle glycogen synthetase". Biochem. Biophys. Res. Commun. 75 (3): 643–50. {{doi|10.1016/0006-291X(77)91521-2}}. PMID 405007.


== Weblinks ==
== Weblinks ==

Version vom 19. Dezember 2014, 17:14 Uhr

Dextrinkette, die durch Glykogen-Synthase verlängert wird

Glykogensynthase oder Stärkesynthase heißen diejenigen Enzyme, die Dextrinketten durch Anhängen eines weiteren Glucose-Moleküls verlängern. Dies ist der vorletzte Schritt in der Synthese von Glykogen und Stärke und daher unentbehrlich für alle Lebewesen, die diese Reservestoffe erzeugen.

Drei verschiedene Typen der Glykogensynthasen sind bekannt: die bakterielle und pflanzliche ADP-Glykogensynthase (EC 2.4.1.21), die pflanzliche körnchengebundene Stärkesynthase (EC 2.4.1.242) und die tierische UDP-Glykogensynthase (EC 2.4.1.11).

Literatur

  • Buschazzio A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM (August 2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation". EMBO J. 23 (16): 3196–3205. doi:10.1038/sj.emboj.7600324. PMC 514502 (freier Volltext). PMID 15272305.; rendered using PyMOL.
  • Jentjens R, Jeukendrup A (2003). "Determinants of post-exercise glycogen synthesis during short-term recovery". Sports Med 33 (2): 117–44. doi:10.2165/00007256-200333020-00004. PMID 12617691.
  • Buchbinder JL, Rath VL, Fletterick RJ (2001). "Structural relationships among regulated and unregulated phosphorylases". Annu Rev Biophys Biomol Struct. 30 (1): 191–209. doi:10.1146/annurev.biophys.30.1.191. PMID 11340058.
  • Buschiazzo A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM (2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.". EMBO J. 23 (16): 3195–205. doi:10.1038/sj.emboj.7600324. PMC 514502 (freier Volltext). PMID 15272305.
  • Coutinho PM, Deleury E, Davies GJ, Henrissat B (2003). "An evolving hierarchical family classification for glycosyltransferases". J. Mol. Biol. 328 (2): 307–17. doi:10.1016/S0022-2836(03)00307-3. PMID 12691742.
  • Roach PJ (2002). "Glycogen and its Metabolism". Curr Mol Med 2 (2): 101–20. doi:10.2174/1566524024605761. PMID 11949930.
  • Ball SG, Morell MK (2003). "From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule". Annu Rev Plant Biol 54 (1): 207–33. doi:10.1146/annurev.arplant.54.031902.134927. PMID 14502990.
  • Azpiazu I, Manchester J, Skurat AV, Roach PJ, Lawrence JC Jr (2000). "Control of glycogen synthesis is shared between glucose transport and glycogen synthase in skeletal muscle fibers". Am J Physiol Endocrinol Metab 278 (2): E234–43. PMID 10662707.
  • Aschenbach WG, Suzuki Y, Breeden K, Prats C, Hirshman MF, Dufresne SD, Sakamoto K, Vilardo PG, Steele M, Kim JH, Jing SL, Goodyear LJ, DePaoli-Roach AA (2001). "The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise". J Biol Chem 276 (43): 39959–67. doi:10.1074/jbc.M105518200. PMID 11522787.
  • Browner MF, Nakano K, Bang AG, Fletterick RJ (March 1989). "Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution". Proceedings of the National Academy of Sciences of the United States of America 86 (5): 1443–7. doi:10.1073/pnas.86.5.1443. PMC 286712 (freier Volltext). PMID 2493642.
  • Westphal SA, Nuttall FQ (February 1992). "Comparative characterization of human and rat liver glycogen synthase". Archives of biochemistry and biophysics 292 (2): 479–86. doi:10.1016/0003-9861(92)90019-S. PMID 1731614.
  • Kollberg G, Tulinius M, Gilljam T, Ostman-Smith I, Forsander G, Jotorp P, Oldfors A, Holme E (October 2007). "Cardiomyopathy and exercise intolerance in muscle glycogen storage disease 0". The New England Journal of Medicine 357 (15): 1507–14. doi:10.1056/NEJMoa066691. PMID 17928598.
  • Huang TS, Krebs EG (April 1977). "Amino acid sequence of a phosphorylation site in skeletal muscle glycogen synthetase". Biochem. Biophys. Res. Commun. 75 (3): 643–50. doi:10.1016/0006-291X(77)91521-2. PMID 405007.

Weblinks

Wikibooks: Biochemie und Pathobiochemie: Glycogensynthese – Lern- und Lehrmaterialien
Abgerufen von „https://de.wikipedia.org/w/index.php?title=Glykogensynthasen&oldid=136928936“