„Granuloma faciale“ – Versionsunterschied
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Version vom 24. Juni 2011, 22:50 Uhr
| Klassifikation nach ICD-10 | |
|---|---|
| L92.2 | Granuloma faciale [Granuloma eosinophilicum faciei] |
| ICD-10 online (WHO-Version 2019) | |
Das Granuloma faciale, auch Granuloma eosinophilicum faciei genannt, ist eine gutartige Gewebeneubildung (Neoplasie).
J. Thiyanaratnam, S. D. Doherty, B. Krishnan, S. Hsu: Granuloma faciale: Case report and review. In: Dermatology online journal Band 15, Nummer 12, 2009, S. 3, ISSN 1087-2108. PMID 20040253. (Review im Open Access).
Beschreibung und Diagnose
First described by Wigley in 1945, this condition is a chronic inflammation of the skin that generally occurs on the nose, chin, forehead, temple or cheeks. [1] Clinically, round or oval brown-red macular and popular lesions with large follicular pores (giving the lesion an orange peel-like appearance) can be observed. Histologically, eosinophilia and patterns of leukocytoclastic vasculitis are characteristic. Therapy consists of dapsone p.o. (100-200 mg/day for four months) or intra-lesional steroid injections (e.g., triamcinolone 10 mg diluted with a local anesthetic 1:3-1:5). Dapsone therapy should be evaluated critically as the results are moderate, and the course of the disease is benign. Recently, the topical preparation of tacrolimus, a macrolide immunosuppressant, has been described as successful.[2] In cases of resistance to conservative therapy, the surgical excision of solitary lesions, cryotherapy, dermabrasion or ablative laser therapy (CO2, argon or erbium: YAG laser) should be considered.[3]
Therapie
Weiterführende Literatur
Einzelnachweise
- ↑ J. E. Wigley: Eosinophilic Granuloma. ? Sarcoid of Boeck. In: Proceedings of the Royal Society of Medicine Band 38, Nummer 3, Januar 1945, S. 125–126, ISSN 0035-9157. PMID 19992999. PMC 218165 (freier Volltext).
- ↑ J. Rieker, U. Hengge, T. Ruzicka, D. Bruch-Gerharz: Multifokales Granuloma eosinophilicum faciei – Erfolgreiche Behandlung mit topischem Tacrolimus. In: Der Hautarzt Band 57, Nummer 4, April 2006, S. 324–326, ISSN 0017-8470. doi:10.1007/s00105-006-1112-0. PMID 16523273.
- ↑ M. Sand, D. Sand, C. Thrandorf, V. Paech, P. Altmeyer, F. G. Bechara: Cutaneous lesions of the nose. In: Head & face medicine Band 6, 2010, S. 7, ISSN 1746-160X. doi:10.1186/1746-160X-6-7. PMID 20525327. PMC 290354 (freier Volltext). (Review im Open Access).
- ↑ C. Patterson, I. Coutts: Granuloma faciale successfully treated with topical tacrolimus. In: The Australasian journal of dermatology Band 50, Nummer 3, August 2009, S. 217–219, ISSN 1440-0960. doi:10.1111/j.1440-0960.2009.00543.x. PMID 19659988. (Review).
- ↑ C. Vente, R. Rupprecht, E. Oestmann, S. Menzel, C. Neumann: Granuloma eosinophilicum faciei – erfolgreiche kryochirurgische Behandlung bei sechs Patienten. In: Der Hautarzt Band 49, Nummer 6, S. 477-481, doi:10.1007/s001050050773, PMID 9675575