Diskussion:Kuru (Krankheit)

Die Übertragbarkeit auf Affen wurde "nachgewiesen", in dem infizierte Hirnmasse wiederum direkt, d. h. intracerebral(!) in ein gesundes Hirn eines lebenden(!) Affen injiziert wurde. Bei oraler Aufnahme von Hirnmasse wurden die Affen nicht infiziert. Somit beweisen diese Experimente so ziemlich nichts. Kuru ist wahrscheinlich eine genetische Krankheit, deren Häufigkeit durch Inzucht gesteigert war. Aber Gajdusek hat den Nobelpreis bekommen, somit sind seine "Forschungsergebnisse" unantastbar. Siehe dazu: Zur Infektiosität der spongiformen Encephalopathien von Professor Dr. med. Roland Scholz. --subsonic68 02:20, 22. Apr 2005 (CEST)

Das Wort "Kuru" stammt aus der Sprache der Eingeborenen und bedeutet übersetzt "Angstzittern". am Anfang, da ist da nur ein leichtes Torkeln. Leichte Koordinationsprobleme. Stück für Stück, über eine Zeitspanne von mehreren Monaten, werden diese Koordinationsprobleme verdammt schwerwiegend. Die Betroffenen sind nicht mehr fähig, ohne Unterstützung alleine zu laufen. Mit der Zeit können sie nicht mal mehr stehen und werden hilflos. Das charakteristische "Zittern" wird immer stärker ausgeprägt. Muskelzuckungen treten auf. Primitive Reflexe (Babinski, etc.) sind auslösbar. Die Betroffenen zeigen eine ziemliche Ausgelassenheit und tun die ganze Zeit crank lachen. Im Endstadium entwickelt sich manchmal eine Demenz. Allerdings erreichte wohl kaum ein Betroffener wirklich das Endstadium, denn im Urwald von Papua Neuguinea gab es keine Magensonden. Und daher verhungerte Der- oder Diejenige vorher.

In Papua Neuguinea gab es wenig Fleisch. Daher litt die Bevölkerung an Proteinmangel. Deswegen fingen die Leute dort damit an, die Verstorbenen zu verspeisen. Denn Menschenfleisch ist sehr nährreich und proteinhaltig. Kuru war mit eine "iatrogen bedingte Creutzfeldt Jakob-Erkrankung". Denn es waren auch die Medizinmänner, die den Eingeborenen rieten, die Gehirne der Verstorbenen zu verspeisen oder sich mit der Gehirnmasse einzureiben. Betroffenen waren vor Allem Frauen und Kinder. Dies lag daran, daß das Muskelfleisch der Toten nur von den Männern verzehrt wurde. Frauen und Kinder mußten sich mit den "schlechteren" Teilen begnügen, wie Hirn und Innereien. Dummerweise enthielten eben genau diese "schlechteren" Teile die meisten Prionen.

Das jüngste Kind, das erkrankte, war gerade mal drei oder vier Jahre alt. Einige Betroffene erkrankten auch noch nach Inkubationszeiten von über 60 Jahren. Bei diesen spät erkrankten handelte es sich interessanterweise um Leute, die allesamt M/V-Heterozygot an Codon 129 des Prion-Protein-Gens waren.

Übersetzung des Textes aus der englischen Wikipedia

Ein großer Teil des Artikels stellt eine Übersetzung aus der englischen WP dar, die mit der deutschen Grundlage zusammengeführt wurde. Die Versionsgeschichte lautet:

   * (cur) (last)  22:04, 18 July 2006 128.6.168.245 (Talk) (→External links)
   * (cur) (last) 17:58, 16 July 2006 24.84.35.186 (Talk) (→The prion protein)
   * (cur) (last) 17:56, 16 July 2006 24.84.35.186 (Talk) (→The prion protein)
   * (cur) (last) 11:20, 27 June 2006 LiniShu (Talk | contribs) m (→Misinterpretations of kuru - spelling)
   * (cur) (last) 17:55, 23 June 2006 Oniongirl (Talk | contribs) (→External links)
   * (cur) (last) 19:37, 31 May 2006 217.132.157.123 (Talk)
   * (cur) (last) 14:58, 30 May 2006 24.180.92.189 (Talk) (→The prion protein)
   * (cur) (last) 14:58, 30 May 2006 24.180.92.189 (Talk) (→The prion protein)
   * (cur) (last) 04:03, 29 May 2006 Sonjaaa (Talk | contribs) (→Kuru among the South Fore)
   * (cur) (last) 06:23, 21 May 2006 Bdelisle (Talk | contribs) (→External links - ICTVdb)
   * (cur) (last) 19:15, 18 May 2006 Kaze0010 (Talk | contribs) m (→The prion protein - scrapie wikipedia link)
   * (cur) (last) 04:21, 6 May 2006 Antandrus (Talk | contribs) m (Reverted edits by 69.107.30.132 (talk) to last version by PS2pcGAMER)
   * (cur) (last) 04:21, 6 May 2006 69.107.30.132 (Talk) (→Kuru among the South Fore)
   * (cur) (last) 05:22, 24 April 2006 PS2pcGAMER (Talk | contribs) m (Reverted edits by 24.34.119.28 (talk) to last version by Kuru)
   * (cur) (last) 05:21, 24 April 2006 24.34.119.28 (Talk)
   * (cur) (last) 05:19, 24 April 2006 Kuru (Talk | contribs) (revert: ok, at least you've got style.)
   * (cur) (last) 05:16, 24 April 2006 24.34.119.28 (Talk)
   * (cur) (last) 02:41, 12 April 2006 69.236.5.249 (Talk) (→Kuru among the South Fore)
   * (cur) (last) 13:20, 23 March 2006 144.134.243.59 (Talk)
   * (cur) (last) 01:39, 14 March 2006 YurikBot (Talk | contribs) m (robot Adding: hr, sv)
   * (cur) (last) 04:10, 5 March 2006 Aechris (Talk | contribs) (→External links)
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   * (cur) (last) 04:07, 5 March 2006 Aechris (Talk | contribs) (→External links)
   * (cur) (last) 22:40, 2 March 2006 Arcadian (Talk | contribs) (clean up using AWB)
   * (cur) (last) 23:20, 19 February 2006 68.195.63.129 (Talk) (→Kuru among the South Fore)
   * (cur) (last) 20:59, 14 February 2006 68.68.89.3 (Talk) (→Symptoms of kuru)
   * (cur) (last) 20:58, 14 February 2006 68.68.89.3 (Talk) (→Symptoms of kuru)
   * (cur) (last) 01:46, 9 February 2006 Chlewbot (Talk | contribs) m (robot Adding: nl)
   * (cur) (last) 00:08, 1 February 2006 24.27.89.188 (Talk) (→Kuru among the South Fore)
   * (cur) (last) 16:33, 31 January 2006 Gdr (Talk | contribs) (remove taxobox: not appropriate since no system (yet) of scientific classification of prions)
   * (cur) (last) 04:28, 18 January 2006 64.126.20.4 (Talk) (→Symptoms of kuru)
   * (cur) (last) 05:00, 10 January 2006 67.170.103.140 (Talk) (→Symptoms of kuru)
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   * (cur) (last) 07:26, 31 December 2005 NTBot (Talk | contribs) m (robot Removing: nl)
   * (cur) (last) 16:24, 23 December 2005 80.186.243.27 (Talk)
   * (cur) (last) 03:54, 23 December 2005 69.194.122.160 (Talk) (Deleted graffitti)
   * (cur) (last) 03:11, 23 December 2005 67.100.203.81 (Talk)
   * (cur) (last) 05:34, 17 December 2005 Bdelisle (Talk | contribs) m (Category:Prions)
   * (cur) (last) 19:57, 2 December 2005 Finlay McWalter (Talk | contribs) m (Reverted edits by 165.155.128.133 (talk) to last version by 24.59.93.186)
   * (cur) (last) 19:54, 2 December 2005 165.155.128.133 (Talk) (→Kuru among the South Fore)
   * (cur) (last) 19:52, 2 December 2005 165.155.128.133 (Talk) (→References)
   * (cur) (last) 15:07, 26 November 2005 24.59.93.186 (Talk)
   * (cur) (last) 12:58, 13 November 2005 Curpsbot-unicodify (Talk | contribs) m (2 &<name>; → Unicode)
   * (cur) (last) 14:23, 20 October 2005 Jfdwolff (Talk | contribs) m (→External links - what's the point)
   * (cur) (last) 12:02, 19 October 2005 213.61.163.194 (Talk) (→External links)
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   * (cur) (last) 04:16, 5 September 2005 Arcadian (Talk | contribs) (infobox)

* (cur) (last) 16:58, 25 August 2005 Postglock (Talk | contribs) (→The prion protein - added

→ Hauptartikel: Prion

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   * (cur) (last) 07:29, 20 August 2005 Ormy (Talk | contribs) m (→Symptoms of kuru)
   * (cur) (last) 07:55, 13 August 2005 FlaBot (Talk | contribs) m (robot Adding: es)
   * (cur) (last) 20:26, 3 August 2005 84.178.147.157 (Talk) (pt:Kuru)
   * (cur) (last) 18:44, 26 July 2005 Maxim Razin (Talk | contribs) m (+ru)
   * (cur) (last) 20:18, 24 July 2005 AHands (Talk | contribs) m (→Kuru among the South Fore)
   * (cur) (last) 20:13, 24 July 2005 AHands (Talk | contribs) m (→The prion protein - link to neurodegenerative disorder)
   * (cur) (last) 17:51, 20 July 2005 134.96.49.34 (Talk)
   * (cur) (last) 23:38, 24 June 2005 69.251.8.209 (Talk) (→The prion protein)
   * (cur) (last) 04:14, 25 May 2005 Alex.tan (Talk | contribs) m (Category:Transmissible spongiform encephalopathies)
   * (cur) (last) 09:10, 22 April 2005 80.55.228.90 (Talk) (pl:)
   * (cur) (last) 17:13, 20 March 2005 81.173.160.82 (Talk) (→Kuru among the South Fore)
   * (cur) (last) 03:04, 21 February 2005 Eras-mus (Talk | contribs)
   * (cur) (last) 05:57, 20 January 2005 Ingoolemo (Talk | contribs) (categorisation)
   * (cur) (last) 07:12, 17 October 2004 ZayZayEM (Talk | contribs) m (wikilinks + certain readibilities)
   * (cur) (last) 21:50, 4 October 2004 217.220.140.253 (Talk)
   * (cur) (last) 01:45, 15 September 2004 Jfdwolff (Talk | contribs) (+cat)
   * (cur) (last) 20:57, 7 September 2004 Sannse (Talk | contribs) m (Disambiguating depression)
   * (cur) (last) 04:47, 5 September 2004 Azhyd (Talk | contribs) (add taxobox)
   * (cur) (last) 09:11, 4 August 2004 Kate (Talk | contribs) m (External links corrections; see User:Kate/extlinks)
   * (cur) (last) 13:36, 30 June 2004 Alex.tan (Talk | contribs) (Category:Infectious diseases)
   * (cur) (last) 23:42, 27 June 2004 Jiang (Talk | contribs) m (tag is for talk pages)
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   * (cur) (last) 11:39, 24 June 2004 OwenBlacker (Talk | contribs) m (→Misinterpretations of kuru - Hyperlinking)
   * (cur) (last) 11:38, 24 June 2004 OwenBlacker (Talk | contribs) m (→The prion protein - Hyperlinking)
   * (cur) (last) 11:35, 24 June 2004 OwenBlacker (Talk | contribs) m (→Symptoms of kuru - Hyperlinking)
   * (cur) (last) 11:32, 24 June 2004 OwenBlacker (Talk | contribs) m (→Kuru among the South Fore - Hyperlinked dates)
   * (cur) (last) 00:27, 22 June 2004 Finlay McWalter (Talk | contribs) m (→Kuru among the South Fore - fmt)
   * (cur) (last) 00:07, 22 June 2004 David Gerard (Talk | contribs) (tighten and clarify intro (whilst avoiding ambiguities flagged in FAC))
   * (cur) (last) 13:55, 21 June 2004 Viz (Talk | contribs) (→Misinterpretations of kuru)
   * (cur) (last) 13:54, 21 June 2004 Viz (Talk | contribs) (→Misinterpretations of kuru)
   * (cur) (last) 13:45, 21 June 2004 Viz (Talk | contribs) (Whose census division?)
   * (cur) (last) 13:43, 21 June 2004 Viz (Talk | contribs) (Grammar edits As well as .... not quite right)
   * (cur) (last) 13:20, 21 June 2004 Viz (Talk | contribs)
   * (cur) (last) 13:19, 21 June 2004 Viz (Talk | contribs)
   * (cur) (last) 13:16, 21 June 2004 Viz (Talk | contribs)
   * (cur) (last) 13:06, 21 June 2004 Viz (Talk | contribs) (→Kuru among the South Fore)
   * (cur) (last) 05:06, 20 June 2004 Neutrality (Talk | contribs) m (Adding featured article candidate message.)
   * (cur) (last) 20:57, 18 June 2004 David Gerard (Talk | contribs) (considerable copyedit and reshuffle)
   * (cur) (last) 09:35, 18 June 2004 Matt Crypto (Talk | contribs) m (don't need an "Introduction" section heading; bld Laughing Sickness)
   * (cur) (last) 21:42, 7 March 2004 65.49.20.154 (Talk)
   * (cur) (last) 00:55, 6 March 2004 Andre Engels (Talk | contribs) m (de: nl:)
   * (cur) (last) 09:30, 5 January 2004 Viz (Talk | contribs) m (GSS spelling correction)
   * (cur) (last) 09:29, 5 January 2004 Viz (Talk | contribs) m (GSS syndrome added umlaut)
   * (cur) (last) 09:24, 5 January 2004 Viz (Talk | contribs) m (GSS syndrome spelling correction)
   * (cur) (last) 09:18, 5 January 2004 Viz (Talk | contribs) m (Creutzfeld-Jakob Disease --> Creutzfeld-Jakob disease)
   * (cur) (last) 09:17, 5 January 2004 Viz (Talk | contribs) m (Line separation between external links)
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   * (cur) (last) 23:47, 2 January 2004 Viz (Talk | contribs) (Links to diseases)
   * (cur) (last) 23:39, 2 January 2004 Viz (Talk | contribs) (Added Acknowledgement)
   * (cur) (last) 23:31, 2 January 2004 Viz (Talk | contribs) (Added External Links/Acknowledgement)
   * (cur) (last) 23:21, 2 January 2004 Viz (Talk | contribs) (Corrected Links and Citation Style)
   * (cur) (last) 23:01, 2 January 2004 Viz (Talk | contribs)
   * (cur) (last) 22:58, 2 January 2004 Viz (Talk | contribs)
   * (cur) (last) 22:56, 2 January 2004 Viz (Talk | contribs)
   * (cur) (last) 22:53, 2 January 2004 Viz (Talk | contribs) (First attempt. Will need Corrections)

Als Übersetzer und Bearbeiter -- トロール 19:21, 22. Jul 2006 (CEST)

Lesenswert-Kandidatur (November 2006) – vorzeitig gescheitert.

Ich bin eben über diesen Artikel gestolpert, der mir sehr gut gefällt. Er enthält eine Menge Details zu der Prionenkrankheit, über die ansonsten nur sehr wenig substantielles zu finden ist.

•  Pro - von mir gibt es deshalb ein pro für die Lesenswerten. -- 89.50.48.198 17:38, 11. Nov. 2006 (CET)
• klares  Kontra! Der Artikel ist nicht besonders gut geschrieben (Leseprobe: Die Frauen entfernten die Arme und Beine und entfernten die Muskeln der Gliedmaßen, danach entfernten sie [...]), der Absatz über Prion ist allgemein und gehört hier im Grunde nicht hin, sondern die Behandlung des Kuru-auslösenden Proteins. Der klinische Aspekt ist praktisch nicht vorhanden, obwohl ich zugebe, dass das bei einer historischen Krankheit nicht an erster Stelle zu stehen braucht. - Gancho Kolloquium 18:02, 11. Nov. 2006 (CET)
•  Kontra Die Gliederung erscheint mir unbefriedigend. Auch der anhang über Prionenerkrankungen an sich wirkt drangeklatscht und beschäftigt sich genaugenommen mit allen möglicvhen Prionenerkrankungen und mit Kuru nur unter ferner liefen. --Kriddl 22:06, 11. Nov. 2006 (CET)
• Dickes Kontra. Sprachlich mangelhaft, viel Geschwurbel (3. Absatz der Einleitung; "Das Prionenprotein": hier schaffen es die Autoren, tatsächlich nichts über das PrP zu verraten.) Die Referenzen nützen niemanden, da keine bibliografischen Angaben zum Wiederauffinden angegeben sind. Entscheidende Fakten, wie die Epidemiologie sind gar nicht referenziert. Hier muss man große Teile wohl neu schreiben und auch neu recherchieren. Zur vergleichenden Lektüre empfehle ich den kürzlich von mir ausgebauten Artikel zur Traberkrankheit (Scrapie), der sicher hier auch bald kandidieren wird.--Uwe G. ¿⇔? 22:27, 11. Nov. 2006 (CET)
• Sorry, aber ich kann mich dem Gesagten nur anschliessen und daher auch meinerseits  Kontra. Für Lesenswert reichts (noch) nicht. --Trinityfolium Anregungen? | Bewerte mich! 00:30, 12. Nov. 2006 (CET)

 Kontra sorry, aber das reicht mir noch nicht: da fehlen echt zu viele medizinische fakten -- die hendrike ♒ 23:44, 12. Nov. 2006 (CET)

• contra, Mangelhafter Import aus en:WP. --Polarlys 15:03, 13. Nov. 2006 (CET)

Vorzeitig gescheitert (24-h-Regelung) --Polarlys 15:03, 13. Nov. 2006 (CET)

Der englische Originalartikel...

... wurde am 7. August 2007 als Urheberrechtsverletzung gelöscht, da die auf der dortigen Diskussionsseite hinterlegte Erlaubnis zur Verwendung eines externen Textes als "Wikipedia-only" eingestuft wurde. Siehe en:Talk:Kuru (disease)#Copyright issues und die Mailingliste. Da dieser Artikel anscheinend eine Übersetzung des englischen Originals ist, betrifft dies auch diese Version hier (es sei denn, hier würde die Erlaubnis als "gut genug" befunden). Lupo 17:16, 8. Aug. 2007 (CEST)

Danke für den Hinweis, Versionslöschung durchgeführt. ––Polarlys 00:55, 10. Okt. 2007 (CEST)

Kuru in Tansania?

Am Anfang des Artikels wird behauptet, dass Kuru auch in Tansania aufgetreten wäre. Alle anderen Berichte über Kuru beschränken die Krankheit dagegen auf Papua-Neuguinea. Dafür gibt es in Tansania eine Stadt, die Kuru heißt. (Quelle: http://www.worldplaces.net/de/tza/16/kuru/). Liegt da eine Verwechslung vor, oder gibt es wirklich eine Quelle über Kuru-Erkrankungen in Tansania? (nicht signierter Beitrag von 84.135.44.124 (Diskussion) 19:29, 23. Mai 2014 (CEST))

Möglicherweise, da Kuru laut Artikel auch Lachkrankheit genannt wird, wurde es mit der Tanganjika-Lachepidemie verwechselt. 217.186.230.36 22:01, 29. Okt. 2016 (CEST)

Übertragung

Was ist nun die Ursache der Übertragung, sind es Viren oder Bakterien in den infizierten Gehirnen die bei Verzehr oder Übertragung die Krankheit auslösen? (nicht signierter Beitrag von 84.179.203.32 (Diskussion) 08:19, 2. Feb. 2022 (CET))